Aim & Background: Multiple Sclerosis is one of the most common inflammatory central nervous system diseases. In patients, there is a defect in apoptotic pathway making T auto reactive cells nonapoptotic and entering to blood stream. Among the genes related to this disease, there is a gene named CD95L involved in apoptosis pathway.Material & Method: In this survey, we included 30 MS patients and 30 healthy controls which were matched by sex and age. Blood was taken from cases and controls with consent. Next, total RNA was extracted and cDNA was synthesized. Then, by TaqMan Real-time PCR technique, the expression level of CD95L and HGPRT genes was evaluated. The results obtained were analyzed by Linreg and Rest softwares.Result: In this study, CD95L expression in MS patients did not show any significant decrease compared to healthy controls (p Value: 0.197). In addition, in comparison of CD95L expression level between men and women no significant decrease was seen (p Value (M): 0.142, p Value (F): 0.156).Conclusion: In this study, no significant difference of CD95L gene expression between multiple sclerosis patients and healthy controls was seen.

Due to the importance of removing strontium ions in nuclear wastes, in the present work, while synthesizing hydroxybenzaldehyde propyltriethoxysilane ((EtO)3Si-HL) and pyridylmethylidene propyltriethoxysilane ((EtO)3Si-L) ligands, we investigated the properties of silica nanoparticles modified with these ligands as solid adsorbents in The removal of strontium ion from the aqueous solution was investigated and parameters such as pH, time, the mass of adsorbent, temperature, and interfering ions were tested. The adsorption behavior of the adsorbents showed that by modifying the surface of the nano adsorbent, the ability of the adsorbents to adsorb strontium ion at pH=6 increased from 6.31% to 86% and 22.11% using the (EtO)3Si-HL and (EtO)3Si-L ligands, respectively. The results of isotherms and adsorption kinetics indicate that the adsorption process follows the Longmuir isotherm and the pseudo-second-order model, respectively. Also, thermodynamic parameters show that strontium removal from the aqueous solution is an endothermic process. The positive entropy values are the driving force behind the adsorption process.

In this research new adsorbents were prepared by modification of surfactant-coated g g-alumina with three ligands; 1- (2-pyridylazo) -2-naphtol (PAN), dithizone (HDZ) and dimetyl golyoxime (DMG). The adsorbents were used for removal and pre-concentration of Pb+2, Cd+2, Ni+2, Cu+2, Co+2. Aqueous solutions of the metal ions were passed through a column filled with the adsorbent and the retained cations were eluted with nitric acid. Recoveries greater than 96% were obtained for most studied cations. The selectivity of the adsorbent was examined in the presence of different interfering cations. The results showed that the synthesized adsorbents posseses good capacity and selectivity for the most studied cations. The reusability test of the adsorbent showed its capability after five adsorption-elution cycles.